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Tomosyn regulates the small RhoA GTPase to control the dendritic stability of neurons and the surface expression of AMPA receptors
14 Berk M, Copolov D, Dean O, Lu K, Jeavons S, Schapkaitz I, Anderson-Hunt M, Judd F, Katz F, Katz P, Ording-Jespersen S, Little J, Conus P, Cuenod M, Do KQ, Busha AI: N- acetyl cysteine as a glutathione precursor for schizophreniaa double-blind, randomized, placebo-controlled trial
[PubMed: 1522745] 434
For instance, blood-borne fibrin is known to activate neurotoxic innate immune responses in multiple sclerosis mice and to stimulate neurotoxic microglial programs in AD mice [130]
Int J Oncol 46:423429
In addition, heterozygous GPx1 +/ mice had augmented endothelial dysfunction, characterized by a decrease in acetylcholine-mediated vasodilator responses, in carotid arteries following exposure to angiotensin II, a known activator of NADPH-oxidase-dependent ROS generation [73]
